Microwave Heating in Organic Synthesis: Decarboxylation of Malonic Acid Derivatives in Water
Cynthia Lynn Zara, Thomas G. Jin, R. J. GIGUERE
Abstract
Cynthia Lynn Zara, Thomas G. Jin, R. J. GIGUERE
Abstract
Microwave heating permits rapid decarboxylation (15 min, 80–98% isolated yields) of malonic acids in water when employing a microwave autoclave mode and high reaction temperature and power (190°C; 800 Watts).
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Microwave heating permits rapid decarboxylation (15 min, 80–98% isolated yields) of malonic acids in water when employing a microwave autoclave mode and high reaction temperature and power (190°C; 800 Watts).
Key concepts: Decarboxylation, Malonic acid, Chemistry, Autoclave, Microwave, Microwave heating, Organic chemistry, Catalysis