Analysis of chitosan by gel permeation chromatography
Katarzyna Zielińska, А. Г. Шостенко, S. Truszkowski
Abstract
Katarzyna Zielińska, А. Г. Шостенко, S. Truszkowski
Abstract
The effect of γ-radiation on the average molecular weight and the molecular-weight distribution of chitosan has been studied. The analysis of samples by gel permeation chromatography/size exclusion chromatography (GPC/SEC) has shown that the amount of high-molecular-weight fractions decreases and the amount of fractions containing low-molecular-weight chitosans (<50 kDa) increases with an increase in the radiation dose. The radiation-chemical yield of degradation is 11.0 particle/100 eV.
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The effect of γ-radiation on the average molecular weight and the molecular-weight distribution of chitosan has been studied. The analysis of samples by gel permeation chromatography/size exclusion chromatography (GPC/SEC) has shown that the amount of high-molecular-weight fractions decreases and the amount of fractions containing low-molecular-weight chitosans (<50 kDa) increases with an increase in the radiation dose. The radiation-chemical yield of degradation is 11.0 particle/100 eV.
Key concepts: Gel permeation chromatography, Chemistry, Size-exclusion chromatography, Chitosan, Molar mass distribution, Chromatography, Yield (engineering), Permeation