In vitro antifungal activities of new imidazole salts towards dermatophytes
Viviana Cristina Tullio, Annamaria Cuffini, Nicola Carlone
Abstract
Viviana Cristina Tullio, Annamaria Cuffini, Nicola Carlone
Abstract
The in vitro activities of two new miconazole and econazole salts with the sulphosalicylic acid against 71 clinical isolates of dermatophytes were evaluated in comparison with those of miconazole, miconazole nitrate, econazole and econazole nitrate. Miconazole sulphosalicylate and econazole sulphosalicylate were equally effective in inhibiting the fungal growth compared with miconazole, econazole, and their nitrates.
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The in vitro activities of two new miconazole and econazole salts with the sulphosalicylic acid against 71 clinical isolates of dermatophytes were evaluated in comparison with those of miconazole, miconazole nitrate, econazole and econazole nitrate. Miconazole sulphosalicylate and econazole sulphosalicylate were equally effective in inhibiting the fungal growth compared with miconazole, econazole, and their nitrates.
Key concepts: Econazole, Miconazole, Miconazole Nitrate, Antifungal, Dermatophyte, Imidazole, Chemistry, In vitro