ScholarLens Back to search
2010•Journal of Evaluation in Clinical PracticeRequires access

Decision modelling of economic evaluation of intervention programme of breast cancer

Jung‐Chen Chang, Tony H‐H. Chen, Stephen W. Duffy, A M-F Yen, Sam L‐S. Chen

Open publisher page 0 citations

Abstract

OBJECTIVES: Economic appraisal of an intervention is a complex and multivariable problem, with probabilistic issues related not only to clinical outcomes but also to costs and willingness to pay. METHODS: We provide a comprehensive framework for economic appraisal of a health intervention to prevent beast cancer mortality, involving probabilistic model of costs as well as of aspects of the disease process. The economic appraisal can give a range of probabilities of cost-effectiveness depending on willingness or ability to pay. RESULTS: We apply the method to the example of polychemotherapy for early breast cancer. Results indicate a 30% probability of cost-effectiveness for a willingness to pay of $ 60,000 per quality-adjusted life-year and around 50% for a threshold of $ 100,000. CONCLUSION: The comprehensive economic appraisal model is a powerful tool for decision making over a range of economic environments.

About this research paper

What this paper is about

OBJECTIVES: Economic appraisal of an intervention is a complex and multivariable problem, with probabilistic issues related not only to clinical outcomes but also to costs and willingness to pay. METHODS: We provide a comprehensive framework for economic appraisal of a health intervention to prevent beast cancer mortality, involving probabilistic model of costs as well as of aspects of the disease process. The economic appraisal can give a range of probabilities of cost-effectiveness depending on willingness or ability to pay. RESULTS: We apply the method to the example of polychemotherapy for early breast cancer. Results indicate a 30% probability of cost-effectiveness for a willingness to pay of $ 60,000 per quality-adjusted life-year and around 50% for a threshold of $ 100,000. CONCLUSION: The comprehensive economic appraisal model is a powerful tool for decision making over a range of economic environments.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVES: Economic appraisal of an intervention is a complex and multivariable problem, with probabilistic issues related not only to clinical outcomes but also to costs and willingness to pay. METHODS: We provide a comprehensive framework for economic appraisal of a health intervention to prevent beast cancer mortality, involving probabilistic model of costs as well as of aspects of the disease process. The economic appraisal can give a range of probabilities of cost-effectiveness depending on willingness or ability to pay. RESULTS: We apply the method to the example of polychemotherapy for early breast cancer. Results indicate a 30% probability of cost-effectiveness for a willingness to pay of $ 60,000 per quality-adjusted life-year and around 50% for a threshold of $ 100,000. CONCLUSION: The comprehensive economic appraisal model is a powerful tool for decision making over a range of economic environments.

Key concepts: Economic appraisal, Economic evaluation, Willingness to pay, Intervention (counseling), Probabilistic logic, Breast cancer, Actuarial science, Medicine

Related papers

Related paper 1Related paper 2
Back to paper searchBrowse research topicsOriginal source
Decision modelling of economic evaluation of intervention programme of breast cancer — Research Paper | ScholarLens