1983•Infection and ImmunityOpen access
Plasmid Coding for Drug Resistance and Production of Heat-Labile and Heat-Stable Toxins Harbored by an Escherichia coli Strain of Human Origin
M. Lourdes M. Silva, Isabel C. A. Scaletsky, M. H. L. Reis, M H T Affonso, Luíz Rachid Trabulsi
Open full text 9 citations
Abstract
In a study of enterotoxigenic strains of Escherichia coli isolated from children with diarrhea in São Paulo, Brazil, a new enterotoxin and antibiotic resistance plasmid that carries heat-labile toxin, heat-stable toxin, and drug resistance genes was found. This is the first such plasmid to be found in a human strain of E. coli. The plasmid is nonconjugative, has a molecular weight of at least 54 x 10(6), and is mobilized by the R plasmid present in the host strain.