ScholarLens Back to search
1970•PEDIATRICSRequires access

HYPERBILIRUBINEMIA AND KERNICTERUS IN SMALL PREMATURE INFANTS

Bruce D. Ackerman, Geraldine Y. Dyer, Mary M. Leydorf

Open publisher page 65 citations

Abstract

Serum bilirubin levels above 15 mg/100 ml occurred in 7 of 54 infants with a birth weight of less than 1,500 gm. Definite or probable kernicterus occurred in five of these seven infants. The maximum level of indirect serum bilirubin in the five infants with kernicterus varied from 18.5 to 20.4 mg/100 ml in three infants and from 22.2 to 23.2 mg/100 ml in two. Exchange transfusions were performed in four of the five infants at levels of 18 to 22 mg/100 ml but were ineffective in preventing kernicterus. Skin hemorrhage appeared to be one of the etiologic factors causing the hyperbilirubinemia in the five infants with kernicterus. Exchange transfusion must be performed at levels of indirect bilirubin below 20 mg/100 ml if death or neurologic damage are to be prevented in the small, critically ill premature infant.

About this research paper

What this paper is about

Serum bilirubin levels above 15 mg/100 ml occurred in 7 of 54 infants with a birth weight of less than 1,500 gm. Definite or probable kernicterus occurred in five of these seven infants. The maximum level of indirect serum bilirubin in the five infants with kernicterus varied from 18.5 to 20.4 mg/100 ml in three infants and from 22.2 to 23.2 mg/100 ml in two. Exchange transfusions were performed in four of the five infants at levels of 18 to 22 mg/100 ml but were ineffective in preventing kernicterus. Skin hemorrhage appeared to be one of the etiologic factors causing the hyperbilirubinemia in the five infants with kernicterus. Exchange transfusion must be performed at levels of indirect bilirubin below 20 mg/100 ml if death or neurologic damage are to be prevented in the small, critically ill premature infant.

Why it matters

OpenAlex reports 65 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Serum bilirubin levels above 15 mg/100 ml occurred in 7 of 54 infants with a birth weight of less than 1,500 gm. Definite or probable kernicterus occurred in five of these seven infants. The maximum level of indirect serum bilirubin in the five infants with kernicterus varied from 18.5 to 20.4 mg/100 ml in three infants and from 22.2 to 23.2 mg/100 ml in two. Exchange transfusions were performed in four of the five infants at levels of 18 to 22 mg/100 ml but were ineffective in preventing kernicterus. Skin hemorrhage appeared to be one of the etiologic factors causing the hyperbilirubinemia in the five infants with kernicterus. Exchange transfusion must be performed at levels of indirect bilirubin below 20 mg/100 ml if death or neurologic damage are to be prevented in the small, critically ill premature infant.

Key concepts: Kernicterus, Medicine, Exchange transfusion, Pediatrics, Serum bilirubin, Bilirubin, Jaundice, Internal medicine

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
HYPERBILIRUBINEMIA AND KERNICTERUS IN SMALL PREMATURE INFANTS — Research Paper | ScholarLens