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2015•Future OncologyRequires access

Obinutuzumab in Chronic Lymphocytic Leukemia

Jehan Dupuis

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Abstract

Obinutuzumab is the second next-generation monoclonal anti-CD20 antibody (after ofatumumab) to enter clinical practice in chronic lymphocytic leukemia. Its superiority in association with chlorambucil as compared with chlorambucil alone has led to its approval as a first-line treatment for chronic lymphocytic leukemia, for patients who are not candidates for a more intensive treatment.

About this research paper

What this paper is about

Obinutuzumab is the second next-generation monoclonal anti-CD20 antibody (after ofatumumab) to enter clinical practice in chronic lymphocytic leukemia. Its superiority in association with chlorambucil as compared with chlorambucil alone has led to its approval as a first-line treatment for chronic lymphocytic leukemia, for patients who are not candidates for a more intensive treatment.

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OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Method / approach

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Available abstract

Obinutuzumab is the second next-generation monoclonal anti-CD20 antibody (after ofatumumab) to enter clinical practice in chronic lymphocytic leukemia. Its superiority in association with chlorambucil as compared with chlorambucil alone has led to its approval as a first-line treatment for chronic lymphocytic leukemia, for patients who are not candidates for a more intensive treatment.

Key concepts: Obinutuzumab, Chlorambucil, Chronic lymphocytic leukemia, Medicine, Ofatumumab, CD20, Oncology, Internal medicine

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