1966•PubMedRequires access
A procedure for the determination of total iodine in radioactive iodide preparations of high specific activity.
R. W. Helmkamp, Ma. de los Angeles Contreras, William F. Bale
Open publisher page 3 citations
Abstract
Summary A method, based on radioactivity measurements, is described for determining total iodine in highly radioactive iodide samples. In 131I-labeling of protein or other substances, by procedures in which 131I as iodide is oxidized to positive iodine, this analysis permits calculation of the amount of iodine incorporated in the labeled product. When the iodinating agent is iodine monochloride, into which 131I is introduced by isotopic exchange, this analysis makes it possible to predict the fraction of the 131I used that will be in the iodinated substance.