1974Acta Medica ScandinavicaRequires access

IDIOPATHIC LIGHT CHAIN DYSCRASIA—A NEW DISTINCT ENTITY?

J Cronstedt, L. Carling, H Östberg

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Abstract

Abstract. A case of IgG and IgM deficiency and Bence Jones proteinuria is reported. Despite the protein abnormalities of light chain disease, the patient lacks other signs of myelomatosis. Since the pattern of immunoglobulin deficiency has remained constant over a 5‐year period and the excretion of light chains amounts to 175 mg/l, the proposal is made that this case represents a hitherto unrecognized type of benign gammapathy.

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Abstract. A case of IgG and IgM deficiency and Bence Jones proteinuria is reported. Despite the protein abnormalities of light chain disease, the patient lacks other signs of myelomatosis. Since the pattern of immunoglobulin deficiency has remained constant over a 5‐year period and the excretion of light chains amounts to 175 mg/l, the proposal is made that this case represents a hitherto unrecognized type of benign gammapathy.

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Available abstract

Abstract. A case of IgG and IgM deficiency and Bence Jones proteinuria is reported. Despite the protein abnormalities of light chain disease, the patient lacks other signs of myelomatosis. Since the pattern of immunoglobulin deficiency has remained constant over a 5‐year period and the excretion of light chains amounts to 175 mg/l, the proposal is made that this case represents a hitherto unrecognized type of benign gammapathy.

Key concepts: Bence Jones protein, Dyscrasia, Plasma cell dyscrasia, Immunoglobulin light chain, Medicine, Proteinuria, Immunoglobulin A, Paraproteinemias

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