2012•PubMedOpen access

Pemphigus Vulgaris Associated with Rheumatoid Arthritis in a Patient not Taking Penicillamine.

Narges Gholizadeh, Ali Taghavi Zenouz, Hosein Eslami

Abstract

D-penicillamine is one of the disease-modifying anti-rheumatic drugs (DMARDs). Drug-induced pemphigus is not fre-quently associated with D-penicillamine, and to date, the number of reported cases is about a hundred. Most reports of D-penicillamine-induced pemphigus vulgaris are in patients with rheumatoid arthritis. It has rarely been reported in patients not taking D-penicillamine. We report a case of pemphigus vulgaris in a 48-year-old female patient with rheumatoid arthri-tis, not taking penicillamine.

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Key concepts: Penicillamine, Pemphigus vulgaris, Rheumatoid arthritis, Medicine, Pemphigus, Dermatology, Autoimmune disease, Disease