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2011•European Journal of DermatologyRequires access

Residents’ corner September 2011. CarpeDIEM – Birbeck granule in Langerhans cell histiocytosis

Emmanuella Guenova, Martin Schaller

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Abstract

ejd.2011.1540 Auteur(s) : Emmanuella Guenova emmanuella.guenova@gmail.com, Martin Schaller Department of Dermatology, University of Tuebingen, Liebermeisterstrasse 25, 72076 Tubingen, Germany Langerhans cell histiocytosis (LCH) is characterized by lesions rich in langerin+ (CD207+)/CD1a+/Birbeck granule+ cells, with a dendritic Langerhans cell (LC) phenotype. The clinical course of the disease may range broadly, from spontaneous remission sometimes to a fatal outcome. Histology and immunocytochemical [...]

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ejd.2011.1540 Auteur(s) : Emmanuella Guenova emmanuella.guenova@gmail.com, Martin Schaller Department of Dermatology, University of Tuebingen, Liebermeisterstrasse 25, 72076 Tubingen, Germany Langerhans cell histiocytosis (LCH) is characterized by lesions rich in langerin+ (CD207+)/CD1a+/Birbeck granule+ cells, with a dendritic Langerhans cell (LC) phenotype. The clinical course of the disease may range broadly, from spontaneous remission sometimes to a fatal outcome. Histology and immunocytochemical [...]

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Available abstract

ejd.2011.1540 Auteur(s) : Emmanuella Guenova emmanuella.guenova@gmail.com, Martin Schaller Department of Dermatology, University of Tuebingen, Liebermeisterstrasse 25, 72076 Tubingen, Germany Langerhans cell histiocytosis (LCH) is characterized by lesions rich in langerin+ (CD207+)/CD1a+/Birbeck granule+ cells, with a dendritic Langerhans cell (LC) phenotype. The clinical course of the disease may range broadly, from spontaneous remission sometimes to a fatal outcome. Histology and immunocytochemical [...]

Key concepts: Birbeck granules, Langerin, Langerhans cell histiocytosis, Langerhans cell, Histiocytosis, Medicine, Pathology, Histiocytosis X

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