2015•RSC AdvancesOpen access

Mechanistic investigations of a bifunctional squaramide organocatalyst in asymmetric Michael reaction and observation of stereoselective retro-Michael reaction

Eszter Varga, László Tamás Mika, Antal Csámpai, Tamás Holczbauer, György Kardos, Tibor Soós

Abstract

The mechanism of cinchona–squaramide organocatalytic Michael addition was studied using in situ IR and NMR experiments. As a result, not only kinetic parameters were determined but a stereoselective retro-Michael reaction was also observed.

Open-access reader

About this research paper

What this paper is about

Why it matters

OpenAlex reports 32 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Squaramide, Michael reaction, Bifunctional, Stereoselectivity, Chemistry, Cinchona, Organocatalysis, Organic chemistry