2015•Malignant tumoursOpen access

Fibroblast growth factor receptors in malignant tumors

М. Yu. Fedyanin, D. N. Hmel’kova, Tatiana Serebriyskaya, Tatiana Nikolskaya, S. А. Tyulyandin

Abstract

One of the most currently studied markers in oncology are receptors for fibroblast growth factor and their ligands. In this review we focus on the molecular processes that occur during the activation of receptors for fibroblast growth factor. And also consider the frequency of disorders of the expression of components of the signaling pathway of this receptor in various types of malignant diseases.

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Key concepts: Fibroblast growth factor receptor, Receptor, Fibroblast growth factor receptor 2, Cancer research, Growth factor receptor inhibitor, Fibroblast growth factor receptor 3, Growth factor receptor, Fibroblast growth factor