Bronchial asthma and allergic rhinitis associated with inhalation of pancreatic extracts.

Five parents of children with cystic fibrosis developed allergic bronchospasm after inhaling pancreatic extracts sprinkled on their children’s food. There was a positive history of allergy, but no past history of asthma in any of the 5 parents. Asthma responded to bronchodilators, and use of a face mask during preparation of meals prevented recurrences. To date, asthma precipitated by inhalation of pancreatic extracts has not been seen in any of the patients with cystic fibrosis.