2002•The Journal of AntibioticsOpen access

Radamycin, a Novel Thiopeptide Produced by Streptomyces sp. RSP9. II. Physico-chemical Properties and Structure Determination.

Julian Castro Rodriguez, Gloria Gonzalez Holgado, Ramón I. Santamaría, Librada M. Cañedo

Abstract

The new cyclic peptide antibiotic, radamycin (1) and the known thiopeptide methylsulfomycin I (2) have been isolated from the fermentation broth of a Streptomyces sp. RSP9. The structure of radamycin was elucidated by NMR, LC-MS and FAB-MS and was established as a thiopeptide with oxazole and thiazole moieties, and several unusual amino acids.

Open-access reader

About this research paper

What this paper is about

Why it matters

OpenAlex reports 20 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Chemistry, Streptomyces, Streptomycetaceae, Stereochemistry, Cyclic peptide, Actinomycetales, Fermentation, Peptide