1981•Infection and ImmunityOpen access
Restoration by Normal Human Immunoglobulin G of Deficient Serum Opsonization for Streptococcus pneumoniae in Sickle Cell Disease
Ann B. Bjornson, Jeffrey S. Lobel, Patricia I. Magnafichi, Beatrice C. Lampkin
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Abstract
Supplementation of sera from four children with sickle cell disease with untreated or heated normal human serum or with normal human immunoglobulin G restored opsonic activity for serotype 10 Streptococcus pneumoniae, whereas supplementation with normal human immunoglobulin M did not.
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