2003•Humana Press eBooksOpen access

Bone Turnover Markers

Richard Eastell, Penny R. Bainbridge

Abstract

Bone turnover markers have been used in medicine for over 70 yr and have proven indispensable in metabolic bone disorders such as Paget’s disease of bone. The perturbations in bone turnover in osteoporosis are small and early markers that are not specific to bone were not very useful in evaluating the disease. However, marker measures have recently been introduced that are more specific for bone. In this chapter, we will consider the approaches for the use of these markers in the evaluation of osteoporosis.

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Key concepts: Bone remodeling, Osteoporosis, Metabolic bone disease, Medicine, Bone histomorphometry, Bone disease, Disease, Internal medicine