Polyoma Virus Infection of Retinoic Acid-Induced Differentiated Teratocarcinoma Cells
Frank K. Fujimura, Pamela E. Silbert, Walter Eckhart, Elwood A. Linney
Abstract
Frank K. Fujimura, Pamela E. Silbert, Walter Eckhart, Elwood A. Linney
Abstract
The mouse teratocarcinoma stem cell line, F9, becomes permissive for productive polyoma infection upon treatment with retinoic acid. Through the use of M13-polyoma recombinant single-stranded DNA probes, spliced and unspliced early viral RNA were detected after polyoma infection of retinoic acid-treated and untreated F9 cultures.
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The mouse teratocarcinoma stem cell line, F9, becomes permissive for productive polyoma infection upon treatment with retinoic acid. Through the use of M13-polyoma recombinant single-stranded DNA probes, spliced and unspliced early viral RNA were detected after polyoma infection of retinoic acid-treated and untreated F9 cultures.
Key concepts: Teratocarcinoma, Retinoic acid, Biology, Recombinant DNA, Cell culture, Molecular biology, Virology, Virus