1981•Journal of VirologyOpen access

Polyoma Virus Infection of Retinoic Acid-Induced Differentiated Teratocarcinoma Cells

Frank K. Fujimura, Pamela E. Silbert, Walter Eckhart, Elwood A. Linney

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Abstract

The mouse teratocarcinoma stem cell line, F9, becomes permissive for productive polyoma infection upon treatment with retinoic acid. Through the use of M13-polyoma recombinant single-stranded DNA probes, spliced and unspliced early viral RNA were detected after polyoma infection of retinoic acid-treated and untreated F9 cultures.

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What this paper is about

The mouse teratocarcinoma stem cell line, F9, becomes permissive for productive polyoma infection upon treatment with retinoic acid. Through the use of M13-polyoma recombinant single-stranded DNA probes, spliced and unspliced early viral RNA were detected after polyoma infection of retinoic acid-treated and untreated F9 cultures.

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Available abstract

The mouse teratocarcinoma stem cell line, F9, becomes permissive for productive polyoma infection upon treatment with retinoic acid. Through the use of M13-polyoma recombinant single-stranded DNA probes, spliced and unspliced early viral RNA were detected after polyoma infection of retinoic acid-treated and untreated F9 cultures.

Key concepts: Teratocarcinoma, Retinoic acid, Biology, Recombinant DNA, Cell culture, Molecular biology, Virology, Virus

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