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Decreased accumulation of isopropyl-lodoamphetamine (I-123) in brain tumors.

Norman LaFrance, H.N. Wagner, Peter J. Whitehouse, E. Corley, Timothy Duelfer

Open publisher page 53 citations

Abstract

Four out of four patients with brain tumors were observed to have impaired N-isopropyl-p-(/sup 123/I)iodoamphetamine (IAMPH) accumulation by the lesions even though brain scans with technetium-99m diethylenetriamine pentaccetic acid were normal in two. IAMPH may be a more sensitive means of detecting regional cerebral disease than tracers primarily sensitive to blood-flow abnormalities or impairment of the blood-brain barrier.

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What this paper is about

Four out of four patients with brain tumors were observed to have impaired N-isopropyl-p-(/sup 123/I)iodoamphetamine (IAMPH) accumulation by the lesions even though brain scans with technetium-99m diethylenetriamine pentaccetic acid were normal in two. IAMPH may be a more sensitive means of detecting regional cerebral disease than tracers primarily sensitive to blood-flow abnormalities or impairment of the blood-brain barrier.

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OpenAlex reports 53 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Four out of four patients with brain tumors were observed to have impaired N-isopropyl-p-(/sup 123/I)iodoamphetamine (IAMPH) accumulation by the lesions even though brain scans with technetium-99m diethylenetriamine pentaccetic acid were normal in two. IAMPH may be a more sensitive means of detecting regional cerebral disease than tracers primarily sensitive to blood-flow abnormalities or impairment of the blood-brain barrier.

Key concepts: Isopropyl, Cerebral blood flow, Medicine, Technetium, Blood–brain barrier, Iodine-123, Pathology, Blood flow

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Decreased accumulation of isopropyl-lodoamphetamine (I-123) in brain tumors. — Research Paper | ScholarLens