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Transcriptomics and Proteomics: Integration?

Bent Honoré, Morten Østergaard

Open publisher page 3 citations

Abstract

Abstract The genes are transcribed to pre‐messenger RNA, further processed to messenger RNA (transcripts), and finally translated into protein. The transcriptome constitutes the complete set of different transcripts that is synthesized in the lifetime of a cell or a tissue. The proteome refers to the complete set of proteins that is expressed, and modified following expression in the lifetime of a cell or a given tissue. Transcriptomics refers to the study of the transcriptome, while proteomics refers to the study of the proteome using large‐scale technologies for transcript or protein analyses. The two disciplines each provide unique information and supplement each other.

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What this paper is about

Abstract The genes are transcribed to pre‐messenger RNA, further processed to messenger RNA (transcripts), and finally translated into protein. The transcriptome constitutes the complete set of different transcripts that is synthesized in the lifetime of a cell or a tissue. The proteome refers to the complete set of proteins that is expressed, and modified following expression in the lifetime of a cell or a given tissue. Transcriptomics refers to the study of the transcriptome, while proteomics refers to the study of the proteome using large‐scale technologies for transcript or protein analyses. The two disciplines each provide unique information and supplement each other.

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Available abstract

Abstract The genes are transcribed to pre‐messenger RNA, further processed to messenger RNA (transcripts), and finally translated into protein. The transcriptome constitutes the complete set of different transcripts that is synthesized in the lifetime of a cell or a tissue. The proteome refers to the complete set of proteins that is expressed, and modified following expression in the lifetime of a cell or a given tissue. Transcriptomics refers to the study of the transcriptome, while proteomics refers to the study of the proteome using large‐scale technologies for transcript or protein analyses. The two disciplines each provide unique information and supplement each other.

Key concepts: Transcriptome, Proteome, Proteomics, Computational biology, Messenger RNA, Biology, RNA-Seq, Gene

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