Synthesis of 4-aminobenzoic acid esters of polyethylene glycol and their use for pegylation of therapeutic proteins
Dmitry V. Lonshakov, S. V. Sheremet’ev, E. M. Belosludtseva, S. A. Korovkin, А. В. Семченко, A. V. Katlinskij
Abstract
Dmitry V. Lonshakov, S. V. Sheremet’ev, E. M. Belosludtseva, S. A. Korovkin, А. В. Семченко, A. V. Katlinskij
Abstract
4-Aminobenzoic acid esters of polyethylene glycol were synthesized and used for pegylation of recombinant human interferon α-2b and erythropoietin β.
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4-Aminobenzoic acid esters of polyethylene glycol were synthesized and used for pegylation of recombinant human interferon α-2b and erythropoietin β.
Key concepts: PEGylation, Polyethylene glycol, Chemistry, Recombinant DNA, Organic chemistry, Biochemistry, Combinatorial chemistry, Gene