FLUCTUATING COURSE OF RED CELL DISTRIBUTION WIDTH IN TREATMENT OF IRON DEFICIENCY ANEMIA AND ITS CLINICAL RELEVANCE
Soner Solmaz, Süheyl Asma, Çiğdem Gereklioğlu, Mutlu Kasar, M. Ilkin Yeral, Can Boğa, Hakan Özdoğu
Abstract
Soner Solmaz, Süheyl Asma, Çiğdem Gereklioğlu, Mutlu Kasar, M. Ilkin Yeral, Can Boğa, Hakan Özdoğu
Abstract
BACKGROUND: Red cell distribution width (RDW) is a routine parameter of blood count. The use of this parameter generally restricted to the differential diagnosis of microcytic anemia. However, there is insufficient published data on the course of RDW in the treatment of iron deficiency anemia and its clinical importance. Therefore, this study investigated the course of RDW in the treatment of iron deficiency anemia and its association with increased hemoglobin values. METHODS: One hundred five patients diagnosed iron deficiency anemia were enrolled in this study. RESULTS: The mean hemoglobin values of patients at diagnosis and at 1, 2 and 3 months after initiation of treatment were 9.2±1.5, 11.7±1.0, 12.7±0.8, and 13.1±0.8 g/dL, respectively. The mean RDW values of patients at diagnosis and 1, 2 and 3 months after initiation of treatment were 18.4±2.6, 26.4±6.5, 17.8±4.3, and 14.7±1.7%, respectively. Between baseline and 1 month of treatment there was a significant increase in RDW values (p
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BACKGROUND: Red cell distribution width (RDW) is a routine parameter of blood count. The use of this parameter generally restricted to the differential diagnosis of microcytic anemia. However, there is insufficient published data on the course of RDW in the treatment of iron deficiency anemia and its clinical importance. Therefore, this study investigated the course of RDW in the treatment of iron deficiency anemia and its association with increased hemoglobin values. METHODS: One hundred five patients diagnosed iron deficiency anemia were enrolled in this study. RESULTS: The mean hemoglobin values of patients at diagnosis and at 1, 2 and 3 months after initiation of treatment were 9.2±1.5, 11.7±1.0, 12.7±0.8, and 13.1±0.8 g/dL, respectively. The mean RDW values of patients at diagnosis and 1, 2 and 3 months after initiation of treatment were 18.4±2.6, 26.4±6.5, 17.8±4.3, and 14.7±1.7%, respectively. Between baseline and 1 month of treatment there was a significant increase in RDW values (p
Key concepts: Red blood cell distribution width, Medicine, Anemia, Iron-deficiency anemia, Hemoglobin, Iron deficiency, Gastroenterology, Internal medicine