2003•Current Protocols in NeuroscienceRequires access

Models of Neuropathic Pain in the Rat

Gary J. Bennett, Jin Mo Chung, Marie P. Honore, Ze’ev Seltzer

Open publisher page 70 citations

Abstract

There are now three models of neuropathic pain in the rat that are in widespread use: the chronic constriction injury, the partial sciatic ligation model, and the spinal nerve ligation model. The procedures to create these models and the behavioral assays used to quantify the resulting abnormal pain sensations are described in this unit.

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What this paper is about

There are now three models of neuropathic pain in the rat that are in widespread use: the chronic constriction injury, the partial sciatic ligation model, and the spinal nerve ligation model. The procedures to create these models and the behavioral assays used to quantify the resulting abnormal pain sensations are described in this unit.

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OpenAlex reports 70 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

There are now three models of neuropathic pain in the rat that are in widespread use: the chronic constriction injury, the partial sciatic ligation model, and the spinal nerve ligation model. The procedures to create these models and the behavioral assays used to quantify the resulting abnormal pain sensations are described in this unit.

Key concepts: Neuropathic pain, Sciatic nerve, Ligation, Rat model, Medicine, Anesthesia, Constriction, Nerve injury

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