Analysis of Pleural Effusions from Rats Exposed to High Concentrations of Oxygen

Abstract Pleural effusions from rats exposed to high concentrations of oxygen for periods of up to 96 hr. were analyzed by routine clinical chemical methods. When compared to control rat serum, the values for glutamic oxalacetic transaminase, the albumin/ globulin ratio, potassium, and inorganic phosphate were higher in the pleural effusions. Alkaline phosphatase, total protein, albumin, and calcium values were higher in the control serum than in the pleural effusions, and there were no significant differences between the two fluids in the levels of lactate dehydrogenase and glutamic pyruvic transaminase.