2015•Iranian journal of medical sciencesOpen access

Antimicrobial Activity of Garlic Extract Against Shigella

Ali Sadeghian, Kiarash Ghazvini

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Abstract

Some beliefs suggest that garlic is an excellent natural antimicrobial drug that can be considered as an alternative form of treatment or prophylaxis in gastrointestinal infections. The purpose of this study is to determine quantitative antimicrobial activity of garlic against Shigella by detecting the MIC . Garlic extracts were obtained and dilution susceptibility assay was used to determine the antibacterial properties of these extracts. A ll tested isolates of Shigella were susceptible to garlic extracts, and no one showed resistance to garlic extracts.  These and many other research works propose garlic as a strategy for a low-cost intervention with few side effects and complete lack of resistance for prophylaxis and remedy of shigellosis in populations at high risk, particularly where antibiotic resistance and the risk of reinfection are high.

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What this paper is about

Some beliefs suggest that garlic is an excellent natural antimicrobial drug that can be considered as an alternative form of treatment or prophylaxis in gastrointestinal infections. The purpose of this study is to determine quantitative antimicrobial activity of garlic against Shigella by detecting the MIC . Garlic extracts were obtained and dilution susceptibility assay was used to determine the antibacterial properties of these extracts. A ll tested isolates of Shigella were susceptible to garlic extracts, and no one showed resistance to garlic extracts.  These and many other research works propose garlic as a strategy for a low-cost intervention with few side effects and complete lack of resistance for prophylaxis and remedy of shigellosis in populations at high risk, particularly where antibiotic resistance and the risk of reinfection are high.

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Available abstract

Some beliefs suggest that garlic is an excellent natural antimicrobial drug that can be considered as an alternative form of treatment or prophylaxis in gastrointestinal infections. The purpose of this study is to determine quantitative antimicrobial activity of garlic against Shigella by detecting the MIC . Garlic extracts were obtained and dilution susceptibility assay was used to determine the antibacterial properties of these extracts. A ll tested isolates of Shigella were susceptible to garlic extracts, and no one showed resistance to garlic extracts.  These and many other research works propose garlic as a strategy for a low-cost intervention with few side effects and complete lack of resistance for prophylaxis and remedy of shigellosis in populations at high risk, particularly where antibiotic resistance and the risk of reinfection are high.

Key concepts: Shigellosis, Medicine, Antimicrobial, Shigella, Antibiotics, Antibiotic resistance, Shigella dysenteriae, Traditional medicine

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