2014•Orvosi HetilapRequires access
Novel treatment opportunities in Graves’ orbitopathy
Annamária Erdei, Annamária Gazdag, Miklós Bodor, Eszter Berta, Mónika Katkó, Bernadett Ujhelyi, Zita Steiber, Ferenc Győry, Hilda Urbancsek, Sándor Kristóf Barna, László Pál Galuska, Valéria Nagy
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Abstract
Graves' orbitopathy is the most common extrathyroidal manifestation of Graves' disease. Up to now, curative treatment modalities for the most severe sight-threatening cases have not been developed. Here the authors summarize the treatment protocol of Graves' orbitopathy and review novel therapeutic options. They review the literature on this topic and present their own clinical experience. The authors point out that anti-CD20 antibody could positively influence the clinical course of Graves' orbitopathy. Selenium is efficient in mild cases. Further prospective investigations are warranted.