2006Encyclopedia of Life SciencesRequires access

Signal Transduction Pathways in Development: the JAK/STAT Pathway

Tetsuji Naka, Tomoharu Ohkawara

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Abstract

Abstract The Janus Kinase (JAK)/signal transducer and achivator of transcription (STAT) pathway is activated not only by various cytokines such as interferon and interleukin, but also by many growth factors. This pathway plays a crucial role in the signal transduction of these factors.

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What this paper is about

Abstract The Janus Kinase (JAK)/signal transducer and achivator of transcription (STAT) pathway is activated not only by various cytokines such as interferon and interleukin, but also by many growth factors. This pathway plays a crucial role in the signal transduction of these factors.

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Available abstract

Abstract The Janus Kinase (JAK)/signal transducer and achivator of transcription (STAT) pathway is activated not only by various cytokines such as interferon and interleukin, but also by many growth factors. This pathway plays a crucial role in the signal transduction of these factors.

Key concepts: Janus kinase, JAK-STAT signaling pathway, stat, Signal transduction, STAT protein, Janus kinase 1, Cell biology, STAT4

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