2006EchocardiographyRequires access

Detection of Impaired Coronary Flow Reserve in Coronary Artery Disease Using Transthoracic Echocardiographic Assessment of Coronary Sinus Blood Flow

Ghasan M. Tabel, Konstantinos Vlachonassios, Mohammed Tabel, Houman Vaghafi, Niveen Abdelmessih, P.A.N. Chandraratna

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Abstract

In order to establish whether coronary flow reserve (CFR) can be measured by transthoracic echocardiography (TTE) with pulse wave Doppler echocardiography, 14 patients with coronary artery disease (CAD) and 12 normal subjects were studied. Coronary sinus blood flow was measured at rest and 2 minutes after intravenous injection of 0.56 mg/kg dipyridamole (DP). CFR was calculated as the DP to rest flow ratio. Patients with CAD were found to have significantly decreased CFR when compared to normal subjects. These findings suggest that TTE may be useful in diagnosing CAD.

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What this paper is about

In order to establish whether coronary flow reserve (CFR) can be measured by transthoracic echocardiography (TTE) with pulse wave Doppler echocardiography, 14 patients with coronary artery disease (CAD) and 12 normal subjects were studied. Coronary sinus blood flow was measured at rest and 2 minutes after intravenous injection of 0.56 mg/kg dipyridamole (DP). CFR was calculated as the DP to rest flow ratio. Patients with CAD were found to have significantly decreased CFR when compared to normal subjects. These findings suggest that TTE may be useful in diagnosing CAD.

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Available abstract

In order to establish whether coronary flow reserve (CFR) can be measured by transthoracic echocardiography (TTE) with pulse wave Doppler echocardiography, 14 patients with coronary artery disease (CAD) and 12 normal subjects were studied. Coronary sinus blood flow was measured at rest and 2 minutes after intravenous injection of 0.56 mg/kg dipyridamole (DP). CFR was calculated as the DP to rest flow ratio. Patients with CAD were found to have significantly decreased CFR when compared to normal subjects. These findings suggest that TTE may be useful in diagnosing CAD.

Key concepts: Coronary flow reserve, Medicine, Cardiology, Internal medicine, Coronary artery disease, Coronary sinus, Dipyridamole, Blood flow

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Detection of Impaired Coronary Flow Reserve in Coronary Artery Disease Using Transthoracic Echocardiographic Assessment of Coronary Sinus Blood Flow — Research Paper | ScholarLens