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[Frontotemporal dementia heterogeneous group of diseases].

Maria Landqvist, Christina Elfgren, Elsabet Englund, Christer Nilsson, Ulla Passant

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Abstract

Frontotemporal lobar degeneration (FTLD) or frontotemporal dementia (FTD) is a clinically and neuropathologically heterogeneous group of primary degenerative dementia diseases. The clinical representation consists of progressive psychiatric and/or neurological symtoms such as behavioural changes, language or motor dysfunction. FTD is usually divided into the following subgroups: Behavioural variant FTD (FTD-bv), semantic dementia (SD), progressive non-fluent aphasia (PNFA) and FTD with motor neuron disease (FTD-MND). Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) show both clinical and neuropathological similarities to FTD, and therefore are often considered being part of the FTD complex. Knowledge about the great diversity in phenotype of FTD facilitates early refererral and diagnosis of patients, which is necessary for adequate support and treatment. (Less)

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Frontotemporal lobar degeneration (FTLD) or frontotemporal dementia (FTD) is a clinically and neuropathologically heterogeneous group of primary degenerative dementia diseases. The clinical representation consists of progressive psychiatric and/or neurological symtoms such as behavioural changes, language or motor dysfunction. FTD is usually divided into the following subgroups: Behavioural variant FTD (FTD-bv), semantic dementia (SD), progressive non-fluent aphasia (PNFA) and FTD with motor neuron disease (FTD-MND). Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) show both clinical and neuropathological similarities to FTD, and therefore are often considered being part of the FTD complex. Knowledge about the great diversity in phenotype of FTD facilitates early refererral and diagnosis of patients, which is necessary for adequate support and treatment. (Less)

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Available abstract

Frontotemporal lobar degeneration (FTLD) or frontotemporal dementia (FTD) is a clinically and neuropathologically heterogeneous group of primary degenerative dementia diseases. The clinical representation consists of progressive psychiatric and/or neurological symtoms such as behavioural changes, language or motor dysfunction. FTD is usually divided into the following subgroups: Behavioural variant FTD (FTD-bv), semantic dementia (SD), progressive non-fluent aphasia (PNFA) and FTD with motor neuron disease (FTD-MND). Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) show both clinical and neuropathological similarities to FTD, and therefore are often considered being part of the FTD complex. Knowledge about the great diversity in phenotype of FTD facilitates early refererral and diagnosis of patients, which is necessary for adequate support and treatment. (Less)

Key concepts: Frontotemporal dementia, Semantic dementia, Primary progressive aphasia, Progressive supranuclear palsy, Frontotemporal lobar degeneration, Corticobasal degeneration, Psychology, Aphasia

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