Efficacy of rituximab in refractory polymyositis.
Olivier Lambotte, Rami R. Kotb, G. Maigné, F.–X. Blanc, Cécile Goujard, Jean François Delfraissy
Abstract
Olivier Lambotte, Rami R. Kotb, G. Maigné, F.–X. Blanc, Cécile Goujard, Jean François Delfraissy
Abstract
We describe the effectiveness of rituximab, an anti-B lymphocyte monoclonal antibody, in a case of refractory polymyositis with interstitial pulmonary disease and anti-Jo-1 autoantibody (antisynthetase syndrome). Rituximab was well tolerated, and its efficacy in inflammatory myositis should be evaluated.
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We describe the effectiveness of rituximab, an anti-B lymphocyte monoclonal antibody, in a case of refractory polymyositis with interstitial pulmonary disease and anti-Jo-1 autoantibody (antisynthetase syndrome). Rituximab was well tolerated, and its efficacy in inflammatory myositis should be evaluated.
Key concepts: Rituximab, Medicine, Polymyositis, Antisynthetase syndrome, Myositis, Refractory (planetary science), Autoantibody, Interstitial lung disease