2000•Drug Metabolism and DispositionRequires access

Studies on the Cytochrome P450 (CYP)-Mediated Metabolic Properties of Miocamycin: Evaluation of the Possibility of a Metabolic Intermediate Complex Formation with CYP, and Identification of the Human CYP Isoforms

Mie Kasahara, Hisashi Suzuki, Izumi Komiya

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Key concepts: CYP3A4, Microsome, Cytochrome P450, Hydroxylation, CYP3A, Unspecific monooxygenase, Ketoconazole, Chemistry

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Studies on the Cytochrome P450 (CYP)-Mediated Metabolic Properties of Miocamycin: Evaluation of the Possibility of a Metabolic Intermediate Complex Formation with CYP, and Identification of the Human CYP Isoforms — Research Paper | ScholarLens