Comparison of patient-controlled sedation using either propofol or propofol-remifentail for ophthalmic operation.

Objective To explore the advantage of patient-controlled sedation(PCS)with propofol and/or remifentanil in ophthalmic operation under retrobulbar nerve block.Methods42 patients with elective ophthalmic operation under retrobulbar nerve block were randomly divided into 3 groups:P group(1% propofol,n=15),R group(0.5%propofol +0.001% remifentanil,n=15)and control group(n=12).Patients in PCS group had medications delivered in LCP fashion by automatic AIPENG pump.Ramsay,cooperation scores,BP,HR,SpO2,RR and AAI were measured during the operation,and the satisfactory scores were measured after the operation.ResultsThere was no significant difference in BP,HR,SpO2 and AAI in all patients(P0.05),RR in R group was lower than that in P group and control group(P0.05).Ramsay,cooperation and satisfactory scores in PCS group were higher than that in control group.There was greater individual variation in terms of propofol and remifentanil consumption in PCS group.No adverse event was observed.ConclusionPatient-controlled sedation with propofol and/or remifentanil can produce satisfied sedation in patients.Continuous monitor is significantly necessary during ophthalmic operation.