1976•Journal of Clinical MicrobiologyOpen access

Immune Response to Acute Otitis Media: Association Between Middle Ear Fluid Antibody and the Clearing of Clinical Infection

John L. Sloyer, Virgil M. Howie, John H. Ploussard, Gerald Schiffman, Richard B. Johnston

Abstract

Clearing of the middle ear fluid in patients with acute otitis media due to Streptococcus pneumoniae or Haemophilus influenzae was significantly associated with the presence and concentration of specific antibody in the middle ear fluid at the time of diagnosis.

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Key concepts: Haemophilus influenzae, Streptococcus pneumoniae, Middle ear, Acute otitis media, Otitis, Antibody, Medicine, Immune system