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2011•Journal of Clinical MicrobiologyOpen access

Detection of an Influenza B Virus Strain with Reduced Susceptibility to Neuraminidase Inhibitor Drugs

Nathalie Bastien, Jonathan B. Gubbay, David Richardson, Katrina Sleeman, Larisa V. Gubareva, Yan Li

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Abstract

The neuraminidase inhibitors (NAIs) oseltamivir and zanamivir have played an essential role in the prophylaxis and treatment of influenza. The residues forming the NA active sites are conserved among influenza A and B viruses ([3][1]). Conserved residues are in direct contact with the substrate or

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What this paper is about

The neuraminidase inhibitors (NAIs) oseltamivir and zanamivir have played an essential role in the prophylaxis and treatment of influenza. The residues forming the NA active sites are conserved among influenza A and B viruses ([3][1]). Conserved residues are in direct contact with the substrate or

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OpenAlex reports 16 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The neuraminidase inhibitors (NAIs) oseltamivir and zanamivir have played an essential role in the prophylaxis and treatment of influenza. The residues forming the NA active sites are conserved among influenza A and B viruses ([3][1]). Conserved residues are in direct contact with the substrate or

Key concepts: Neuraminidase inhibitor, Neuraminidase, Virology, Strain (injury), Influenzavirus B, Microbiology, Orthomyxoviridae, Zanamivir

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