2015•European Journal of Organic ChemistryOpen access

Chemoselective Pd‐Catalyzed Isocyanide Insertion Reaction of Enaminones by C–H Functionalization: Hydrolysis or Cyclization through 1,3‐Palladium Migration

Zheng‐Yang Gu, Xiang Wang, Jia‐Jia Cao, Shun‐Yi Wang, Shun‐Jun Ji

Abstract

Abstract A chemoselective palladium‐catalyzed isocyanide insertion reaction of enaminones was developed. Amide derivatives were synthesized by this C–H functionalization and subsequent hydrolysis reactions. 4‐Aminoquinoline derivatives were prepared by this C–H functionalization, which includes a 1,3‐palladium migration in the process.

Open-access reader

About this research paper

What this paper is about

Why it matters

OpenAlex reports 24 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Chemistry, Palladium, Isocyanide, Surface modification, Amide, Catalysis, Hydrolysis, Combinatorial chemistry