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The effect of passive immunization against tetanus toxoid in man.

M. PLASSARA, C Mandalenaki, E Papathanassiou, Efi Vrachnou, P. Athanassiades

Abstract

The present study deals with the immunological response in man after passive immunization against tetanus toxoid. Treatment of man with equine antitetanus serum stimulates a rise of E rosette-forming T lymphocytes. The level of IgG also rises while the level of IgM falls. It is assumed that the foreign globulin acts as an antigen that evokes the T lymphocytes' co-operation for the humoral immune response with a switch from IgM to IgG synthesis.

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Available abstract

Key concepts: Toxoid, Tetanus, Immunization, Immunology, Antigen, Immune system, Antibody, Gamma globulin