Lymphoepithelioma-like Carcinoma of the Uterine Cervix
Fernando López‐Ríos, Pilar San Miguel, Carmen Bellas, Claudio Ballestı́n, Lucía Hernández
Abstract
Fernando López‐Ríos, Pilar San Miguel, Carmen Bellas, Claudio Ballestı́n, Lucía Hernández
Abstract
Lymphoepithelioma-like carcinomas have been reported outside the nasopharynx in many sites, including the uterine cervix. The association with the Epstein-Barr virus in the latter site is still controversial. To date, Epstein-Barr virus genome has only been demonstrated in Asian patients. We report a case of lymphoepithelioma-like carcinoma of the uterine cervix in a white woman in whom the Epstein-Barr virus infection was tested for by in situ hybridization and polymerase chain reaction. The results of both techniques were negative. Our case and a review of the literature support the contention that cervical lymphoepithelioma-like carcinoma is not associated with Epstein-Barr virus infection in non-Asian patients.
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Lymphoepithelioma-like carcinomas have been reported outside the nasopharynx in many sites, including the uterine cervix. The association with the Epstein-Barr virus in the latter site is still controversial. To date, Epstein-Barr virus genome has only been demonstrated in Asian patients. We report a case of lymphoepithelioma-like carcinoma of the uterine cervix in a white woman in whom the Epstein-Barr virus infection was tested for by in situ hybridization and polymerase chain reaction. The results of both techniques were negative. Our case and a review of the literature support the contention that cervical lymphoepithelioma-like carcinoma is not associated with Epstein-Barr virus infection in non-Asian patients.
Key concepts: Lymphoepithelioma-like carcinoma, Uterine cervix, Carcinoma, Medicine, Gynecology, Cervix, Pathology, Internal medicine