Efficacy of Ivermectin in an injectable formulation against gastrointestinal nematodes of donkeys (Equus asinus)

The efficacy of Ivermectin was evaluated under field conditions at Nyala town, South Darfur State, Sudan. The study involved 16 donkeys. Ivermectin was administered by intramuscular injection at dose of 0.2 mg/kg in the lateral mid- line of the neck. Treatment efficacy was based on the mean faecal egg count reduction 14 days post treatment. A faecal egg count reduction of 100% was found after treatment with Ivermectin. In addition efficacy percentages of Ivermectin against immature and adult nematodes were as follows: Trichostrongylus axei 100%, Parascaris equorum 100%, Oxyuris equi 100%, Triodontophorus sp. 100%, Strongylus sp. 100%, and small strongyles 100%. Two of the control donkeys were infected with Strongylus vulgaris larvae. Ivermectin showed moderate efficacy (69.23%) against larvae found in the mesenteric artery aneurisms. No adverse reactions were observed during the experimental period.