1999•PubMedRequires access

[The SAPHO syndrome: a study of 16 cases].

Alejandro Olivé, Ricard Pérez-Andrés, A. Rivas, Susana Holgado, E. Casado, Mónica Gumá, X Tena

Abstract

The SAPHO syndrome is characterized by synovitis, acne, palmo-plantar pustulosis, hyperostosis and osteitis. SAPHO syndrome has been occasionally described in Spain. We present our experience of 16 cases with the SAPHO syndrome diagnosed between 1984-1995. The predominant clinical symptoms were: anterior thoracic pain (14 cases), sacroiliac pain (7 cases) and peripheral arthritis (2 cases). Cutaneous involvement was characterized by palmo-plantar pustulosis (8 cases) acne (3 cases) and psoriasis (2 cases). The histocompatibility antigen B27 was negative in all cases. A computerized tomographic study revealed involvement of sterno-costo-clavicular and manubriosternal joints (14 cases) and sacroiliitis (8 cases).

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Key concepts: SAPHO syndrome, Medicine, Pustulosis, Hyperostosis, Sacroiliitis, Osteitis, Synovitis, Dermatology