1999•NatureRequires access

A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

Bart De Strooper, Wim G. Annaert, Philippe Cupers, Paul Säftig, Katleen Craessaerts, Jeff S. Mumm, Eric H. Schroeter, Vincent Schrijvers, Michael S. Wolfe, William J. Ray, Alison Goate, Raphael Kopan

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Key concepts: Presenilin, Notch signaling pathway, Amyloid precursor protein secretase, Notch proteins, Cell biology, Notch 1, Biology, Transmembrane protein

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A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain — Research Paper | ScholarLens