Molecular Evolution of Aminoacyl tRNA Synthetases and Origin of Universal Genetic Code
Masa Ishigami, Hideshi Ihara, Hiroyuki Shinoda
Abstract
Masa Ishigami, Hideshi Ihara, Hiroyuki Shinoda
Abstract
Abstract It is thought that living things first appeared on the primitive earth 35 hundred million years ago. At that time, a primitive protein synthesis mechanism was thought to have been established, a genetic code system evolved, and a universal genetic code system developed. Aminoacyl tRNA synthetase must have evolved with the genetic code system. The aim of the present study is to clarify the evolution of aminoacyl tRNA synthetase and the process and era of the establishment of the universal genetic code system.
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Abstract It is thought that living things first appeared on the primitive earth 35 hundred million years ago. At that time, a primitive protein synthesis mechanism was thought to have been established, a genetic code system evolved, and a universal genetic code system developed. Aminoacyl tRNA synthetase must have evolved with the genetic code system. The aim of the present study is to clarify the evolution of aminoacyl tRNA synthetase and the process and era of the establishment of the universal genetic code system.
Key concepts: Genetic code, Aminoacyl tRNA synthetase, Transfer RNA, Genetics, Biology, Evolutionary biology, Computational biology, DNA