1959Biochemical JournalOpen access

Experiments on the origin of oak-bark tannin

D. E. Hathway

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Abstract

5. Sodium salicylate and sodium thiopentone depressed the 32p uptake of 2:3-diphosphoglycerate and adenosine triphosphate to a greater extent than they depressed the 32P exchange of inorganic phos- phate and hexose monophosphate.These agents do not depress 32p uptake by inhibiting triose phosphate dehydrogenase, for neither drug had any effect on glycolysis.The effects of 2:4-dinitrophenol and phenylbutazone resembled those of sodium salicylate and sodium thiopentone on the 32p uptake of the phosphate fractions.I wish to express my gratitude to Professor M. Weatherall for his constant advice and encouragement during the course of the research described in this paper, to Drs M. W. Neil and C. W. Parr for many helpful discussions

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5. Sodium salicylate and sodium thiopentone depressed the 32p uptake of 2:3-diphosphoglycerate and adenosine triphosphate to a greater extent than they depressed the 32P exchange of inorganic phos- phate and hexose monophosphate.These agents do not depress 32p uptake by inhibiting triose phosphate dehydrogenase, for neither drug had any effect on glycolysis.The effects of 2:4-dinitrophenol and phenylbutazone resembled those of sodium salicylate and sodium thiopentone on the 32p uptake of the phosphate fractions.I wish to express my gratitude to Professor M. Weatherall for his constant advice and encouragement during the course of the research described in this paper, to Drs M. W. Neil and C. W. Parr for many helpful discussions

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5. Sodium salicylate and sodium thiopentone depressed the 32p uptake of 2:3-diphosphoglycerate and adenosine triphosphate to a greater extent than they depressed the 32P exchange of inorganic phos- phate and hexose monophosphate.These agents do not depress 32p uptake by inhibiting triose phosphate dehydrogenase, for neither drug had any effect on glycolysis.The effects of 2:4-dinitrophenol and phenylbutazone resembled those of sodium salicylate and sodium thiopentone on the 32p uptake of the phosphate fractions.I wish to express my gratitude to Professor M. Weatherall for his constant advice and encouragement during the course of the research described in this paper, to Drs M. W. Neil and C. W. Parr for many helpful discussions

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