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[Studies on chemical constituents from flowers of Chrysanthemum indicum].

Meihua Gao, Hua Li, Zhang Li, Xiao Shu-xiong

Abstract

OBJECTIVE: To study the chemical constituents of the flowers of Chrysanthemum indicum. METHODS: Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. The structures were identified by means of physico-chemical and spectral data. RESULTS: From the 80% ethanol extract of the material, seven compounds were isolated. Their structures were identified as acacetin(1), acacetin-7-O-(6"-O-acetyl) beta-D-glucopyranoside (2), linarin (3), apigenin-7-O-beta-D-glucopyranoside(4), chlorogenic acid (5), vanillic acid(6) and sucrose(7), respectively. CONCLUSION: Compounds 2, 4, 6 and 7 are isolated from C. indicum for the first time.

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Key concepts: Acacetin, Chlorogenic acid, Chemistry, Apigenin, Vanillic acid, Sephadex, Column chromatography, Silica gel