Protein Folding and Chaperones
R. John Ellis, F‐Ulrich Hartl
Abstract
R. John Ellis, F‐Ulrich Hartl
Abstract
Abstract The specific conformation characteristic of each protein is determined by the amino acid sequence of that protein by the process of protein folding. Molecular chaperones use two distinct mechanisms to prevent premature folding and aggregation by a subset of newly synthesized proteins.
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Abstract The specific conformation characteristic of each protein is determined by the amino acid sequence of that protein by the process of protein folding. Molecular chaperones use two distinct mechanisms to prevent premature folding and aggregation by a subset of newly synthesized proteins.
Key concepts: Protein folding, Folding (DSP implementation), Co-chaperone, Chemistry, Sequence (biology), Chaperone (clinical), Computational biology, Peptide sequence