2006Encyclopedia of Life SciencesRequires access

Protein Folding and Chaperones

R. John Ellis, F‐Ulrich Hartl

Open publisher page 4 citations

Abstract

Abstract The specific conformation characteristic of each protein is determined by the amino acid sequence of that protein by the process of protein folding. Molecular chaperones use two distinct mechanisms to prevent premature folding and aggregation by a subset of newly synthesized proteins.

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What this paper is about

Abstract The specific conformation characteristic of each protein is determined by the amino acid sequence of that protein by the process of protein folding. Molecular chaperones use two distinct mechanisms to prevent premature folding and aggregation by a subset of newly synthesized proteins.

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Available abstract

Abstract The specific conformation characteristic of each protein is determined by the amino acid sequence of that protein by the process of protein folding. Molecular chaperones use two distinct mechanisms to prevent premature folding and aggregation by a subset of newly synthesized proteins.

Key concepts: Protein folding, Folding (DSP implementation), Co-chaperone, Chemistry, Sequence (biology), Chaperone (clinical), Computational biology, Peptide sequence

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