1980•PubMedOpen access

The role of Ca2+ as a trigger for the membrane fusion

Manfred Gratzl, Roland Ekerdt, Gerhard Dahl

Abstract

As revealed by freeze-fracturing, secretory vesicles isolated from pancreatic islet cells fuse when incubated with low concentration of Ca2+. The properties of this process are described and were found to be similar to those investigated with isolated secretory vesicles from different tissue origin. Secretory vesicle fusion is compared mainly with the ionic requirements of insulin secretion by the pancreatic B-cells and exocytosis by other secretory cells.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 5 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Exocytosis, Secretory Vesicle, Vesicle, Secretion, Cell biology, Secretory pathway, Vesicle fusion, Pancreatic islets