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2004•The Thai Journal of Veterinary MedicineOpen access

THE ESTIMATION OF GLOMERULAR FILTRATION RATES USING ENDOGENOUS CREATININE CLEARANCE IN NINE DOGS

Chollada Buranakarl, Wanchai Yenpetch, Siram Suvarnavibhaja

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Abstract

The objective of this study was to estimate the glomerular filtration rates of normal dogs using the clearance of endogenous creatinine, and comparing it to the clearance of exogenous creatinine. Nine healthy dogs, of both sexes, were used in this study. The results showed a significant relationship, with a correlation coefficient = 0.714 (p<0.05). The regression line was an endogenous creatinine clearance = (-0.803 + 0.677) x exogenous creatinine clearance. The use of endogenous creatinine clearance is a simple and convenient method without the need to administer any substances and can be used to evaluate renal function in clinical practice.

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What this paper is about

The objective of this study was to estimate the glomerular filtration rates of normal dogs using the clearance of endogenous creatinine, and comparing it to the clearance of exogenous creatinine. Nine healthy dogs, of both sexes, were used in this study. The results showed a significant relationship, with a correlation coefficient = 0.714 (p<0.05). The regression line was an endogenous creatinine clearance = (-0.803 + 0.677) x exogenous creatinine clearance. The use of endogenous creatinine clearance is a simple and convenient method without the need to administer any substances and can be used to evaluate renal function in clinical practice.

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Available abstract

The objective of this study was to estimate the glomerular filtration rates of normal dogs using the clearance of endogenous creatinine, and comparing it to the clearance of exogenous creatinine. Nine healthy dogs, of both sexes, were used in this study. The results showed a significant relationship, with a correlation coefficient = 0.714 (p<0.05). The regression line was an endogenous creatinine clearance = (-0.803 + 0.677) x exogenous creatinine clearance. The use of endogenous creatinine clearance is a simple and convenient method without the need to administer any substances and can be used to evaluate renal function in clinical practice.

Key concepts: Renal function, Creatinine, Endogeny, Urology, Internal medicine, Medicine, Endocrinology, Clearance

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