Biological Energy Conservation: Oxidative Phosphorylation

1 An Introduction to Bioenergetics.- 1.1 The Flow of Energy and Materials in Biology.- 1.2 Adenosine 5?-triphosphate (ATP).- 1.3 Phosphoryl Transfer Reactions.- 1.4 Substrate-Level Phosphorylation.- 1.5 Oxidation - Reduction Reactions.- 1.6 Respiration and Oxidative Phosphorylation.- 2 The Components of the Respiratory Chain.- 2.1 Nicotinamide Nucleotides.- 2.2 Nicotinamide Nucleotide Transhydrogenase.- 2.3 Respiratory Chain Dehydrogenases.- 2.4 Ubiquinone.- 2.5 Cytochromes.- 2.6 The Composition and Reconstitution of the Respiratory Chain.- 2.7 Spectrophotometric Analyses.- 2.8 Bacterial Respiratory Chains.- 2.9 Electron and Hydrogen Transfer.- 3 The Organization and Function of the Coupling Membrane.- 3.1 Mitochondrial Structure and Function.- 3.2 The Organization of the Mitochondrial Energy Conservation System.- 3.3 Mitochondrial Solute Transport.- 3.4 The Morphology and Organization of the Bacterial Coupling Membrane.- 3.5 Bacterial Solute Transport.- 4 Energy Coupling.- 4.1 Energy Coupling Sites.- 4.2 Respiratory Control.- 4.3 Crossover Points.- 4.4 Uncoupling Agents.- 4.5 Phosphorylation Inhibitors.- 4.6 Reversed Electron Transfer.- 4.7 The Energized State.- 5 Mechanisms of Oxidative Phosphorylation.- 5.1 The Chemical Hypothesis.- 5.2 The Chemiosmotic Hypothesis.- 5.3 The Localized Proton Hypothesis.- 5.4 The Conformational Hypothesis.- 5.5 Chemiosmotic, Localized Proton or Conformational Hypothesis?.- Suggestions for Further Reading.