2011•Journal of Postgraduate Medical InstituteOpen access

Retaliation of Salmonella

Jahanzeb Khan, Parwez Sajad Khan, Abid Jamil

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Abstract

typhoid fever is endemic in developing countries because of the non availability of clean drinking water. Blood cultures on pyrexial patients were done. Of the 25 blood cultures, 24 yielded growth of salmonella typhi and one paratyphi A. The isolates were sensitive to quinolones (100%), 3rd generation cephalosporins (95%), astreonam (76%), amoxycillin and chloramphenicol (20%) and SMZ-TMP (0%). from eighty to hundred percent patients improved with quinolones, 50% with 13 cholramphenicol, 20% with Ceftriaxone and none with amoycillin. Withe the rising resistance of Salmonella to the currently available new toxic and expensive drugs we should adopt basic hygienic principles rather than spend time and money on drugs.

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What this paper is about

typhoid fever is endemic in developing countries because of the non availability of clean drinking water. Blood cultures on pyrexial patients were done. Of the 25 blood cultures, 24 yielded growth of salmonella typhi and one paratyphi A. The isolates were sensitive to quinolones (100%), 3rd generation cephalosporins (95%), astreonam (76%), amoxycillin and chloramphenicol (20%) and SMZ-TMP (0%). from eighty to hundred percent patients improved with quinolones, 50% with 13 cholramphenicol, 20% with Ceftriaxone and none with amoycillin. Withe the rising resistance of Salmonella to the currently available new toxic and expensive drugs we should adopt basic hygienic principles rather than spend time and money on drugs.

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Available abstract

typhoid fever is endemic in developing countries because of the non availability of clean drinking water. Blood cultures on pyrexial patients were done. Of the 25 blood cultures, 24 yielded growth of salmonella typhi and one paratyphi A. The isolates were sensitive to quinolones (100%), 3rd generation cephalosporins (95%), astreonam (76%), amoxycillin and chloramphenicol (20%) and SMZ-TMP (0%). from eighty to hundred percent patients improved with quinolones, 50% with 13 cholramphenicol, 20% with Ceftriaxone and none with amoycillin. Withe the rising resistance of Salmonella to the currently available new toxic and expensive drugs we should adopt basic hygienic principles rather than spend time and money on drugs.

Key concepts: Typhoid fever, Medicine, Ceftriaxone, Salmonella typhi, Salmonella, Chloramphenicol, Cephalosporin, Blood culture

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