Verapamil versus nifedipine in slow-release preparations for the treatment of mild to moderate hypertension.
Ari Shamiss, Simcha Meisel, Naomi Nussinovitch, Talma Rosenthal
Abstract
Ari Shamiss, Simcha Meisel, Naomi Nussinovitch, Talma Rosenthal
Abstract
A crossover study with 24-hour ambulatory blood pressure monitoring was conducted on 30 hypertensive patients, using slow-release preparations of verapamil and nifedipine. Both drugs proved effective hypotensive agents. Nifedipine was slightly, but not significantly, more potent. Fewer side effects were observed with verapamil, but both drugs were well tolerated.
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A crossover study with 24-hour ambulatory blood pressure monitoring was conducted on 30 hypertensive patients, using slow-release preparations of verapamil and nifedipine. Both drugs proved effective hypotensive agents. Nifedipine was slightly, but not significantly, more potent. Fewer side effects were observed with verapamil, but both drugs were well tolerated.
Key concepts: Nifedipine, Verapamil, Medicine, Crossover study, Ambulatory, Blood pressure, Pharmacology, Ambulatory blood pressure