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Efficacy of Moxidectin Against Gastrointestinal Nematodes in Naturally Infected Lambs and Calves

Erkut Tüzer, Müfit Toparlak, Kamil Göksu

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Abstract

In this trial based on the reduction of the egg output and on the evaluation of results from larval/egg differentiation, moxidectin (Cydectin, 1% injectable moxidectin) administrated subcutaneously at a dose of 0.2 mg kgbw -1 was found effective on the gastrointestinal nematodes in naturally infected lambs (8 female and 7 male treatment; 8 female and 7 male control) harbored Haemonchus spp, Ostertagia spp, Trichostrongylus spp and Nematodirus spp and in naturally infected female calves (20 treatment and 10 control) harbored Haemonchus spp, Ostertagia spp, Trichostrongylus spp, Bunostomum sppand Cooperia spp.The efficacy was 100% on day +7, 99.9% on day +14 and 100% on day +28 in lambs and 100% on day +7, 99.9% on day +14 and 98.9% on day +28 in calves. No side effect of the drug was observed.

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What this paper is about

In this trial based on the reduction of the egg output and on the evaluation of results from larval/egg differentiation, moxidectin (Cydectin, 1% injectable moxidectin) administrated subcutaneously at a dose of 0.2 mg kgbw -1 was found effective on the gastrointestinal nematodes in naturally infected lambs (8 female and 7 male treatment; 8 female and 7 male control) harbored Haemonchus spp, Ostertagia spp, Trichostrongylus spp and Nematodirus spp and in naturally infected female calves (20 treatment and 10 control) harbored Haemonchus spp, Ostertagia spp, Trichostrongylus spp, Bunostomum sppand Cooperia spp.The efficacy was 100% on day +7, 99.9% on day +14 and 100% on day +28 in lambs and 100% on day +7, 99.9% on day +14 and 98.9% on day +28 in calves. No side effect of the drug was observed.

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Available abstract

In this trial based on the reduction of the egg output and on the evaluation of results from larval/egg differentiation, moxidectin (Cydectin, 1% injectable moxidectin) administrated subcutaneously at a dose of 0.2 mg kgbw -1 was found effective on the gastrointestinal nematodes in naturally infected lambs (8 female and 7 male treatment; 8 female and 7 male control) harbored Haemonchus spp, Ostertagia spp, Trichostrongylus spp and Nematodirus spp and in naturally infected female calves (20 treatment and 10 control) harbored Haemonchus spp, Ostertagia spp, Trichostrongylus spp, Bunostomum sppand Cooperia spp.The efficacy was 100% on day +7, 99.9% on day +14 and 100% on day +28 in lambs and 100% on day +7, 99.9% on day +14 and 98.9% on day +28 in calves. No side effect of the drug was observed.

Key concepts: Moxidectin, Ostertagia, Nematodirus, Trichostrongylus, Biology, Ostertagia ostertagi, Veterinary medicine, Haemonchus contortus

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